South Plains Crossing is a 144,241 sq. ft. regional shopping center located in Lubbock, Texas, home to Texas Tech University. The center is strategically located near the southwest corner of Slide Road and South Loop 289, Lubbock's premier retail intersection, and benefits from an expanded 28-county trade area comprising over 640,000 people. The shopping center is anchored by Hobby Lobby, Spec's Liquor, and VisionMart. Other tenants in the center include Red Raider Outfitter, Merle Norman cosmetics, Fun Noodle Bar, Painting With a Twist, CE Blades, Weight Watchers, and One Main Financial. Restaurants on outparcels include Chick-fil-A and Cotton Patch.

South Plains Mall, a regional 1.7 million square foot enclosed shopping mall, is located across from the center and is anchored by Dillards, JCPenney, Barnes & Noble, and Premier Cinemas 16. Other national retailers in close proximity include Michael's, Old Navy, Ross, TJ Maxx, PetSmart, OfficeMax, and Mattress Firm.