Seize this rare opportunity to own a 1.36-acre corner lot in the heart of the Onondaga Hill Business District (OHB), a high-traffic, highly visible corridor offering unmatched accessibility and growth potential. With traffic light access and the option for additional acreage, this property is ideal for offices, retail, medical facilities, restaurants (no drive-throughs), libraries, day-care centers, and more-subject to site plan review. The sale includes two adjoining parcels (4811 Makyes Rd - Tax ID 314200-029-000-0002-005-000-0000 and 4794 W. Seneca Tpke - Tax ID 314200-029-000-0002-004-000-0000), providing flexibility and expansion opportunities. While traditional 'home occupations are not generally listed among permitted uses, the zoning does allow for single-family dwellings and family day care, suggesting potential for certain in-home business functions. Don't miss this chance to establish or expand your business or investment in one of Syracuse's most sought-after commercial districts-your business deserves the best, and this is it!