To get from downtown Houston, TX to 16738 Alief Clodine Rd, you can follow these driving directions: Use the right lane to merge onto I-45 S via the ramp to Galveston. Continue on I-45 S and take exit 46B for US-59 S toward Victoria. Merge onto I-69/US-59 S. Take the exit toward Beltway 8 W/Sam Houston Tollway. Keep left at the fork to continue toward Sam Houston Tollway W. Merge onto Sam Houston Tollway W. Take the exit toward Westpark Tollway W. Merge onto Westpark Tollway W. Take the exit toward Eldridge Pkwy. Merge onto Westpark Tollway Frontage Rd W. Turn left onto Eldridge Pkwy. Turn right onto Alief Clodine Rd. These directions are approximate and may vary based on traffic conditions and any road closures. It's always a good idea to double-check your route using a GPS or mapping service before starting your journey.